Fraunhofer Health

Health research at Fraunhofer addresses the four key areas of medical science — drugs, diagnostics, devices and data, or 4D for short. Many innovations emerge at the interface between medical science, natural science, computer science and engineering. With its emphasis on transdisciplinary research, the Fraunhofer-Gesellschaft offers the perfect environment for close collaboration on health research and the development of cost-intelligent precision medicine for the benefit of patients.

News

 

Fraunhofer Institute for Translational Medicine and Pharmacology ITMP

Preclinical research on rare, early-onset diseases in children

From molecules to realistic therapeutic approaches: Fraunhofer ITMP receives funding for three translational projects developing new treatment methods for rare, hard-to-treat diseases in infancy or early childhood.

 

Fraunhofer Institute for Cell Therapy and Immunology IZI

New Toothpaste Stops Periodontal Pathogens

Periodontitis is widespread and can have serious consequences for overall health. Researchers at Fraunhofer have identified a substance that selectively inhibits only those bacteria that cause periodontitis, thereby preserving the natural balance of the oral microbiome. This technology has been further developed and commercialized as a range of oral care products by the spin-off company PerioTrap.

 

Fraunhofer Institute for Toxicology and Experimental Medicine ITEM

Researchers from Fraunhofer ITEM and MHH Receive the Lower Saxony Innovation Award 2025

The collaborative project “iGUARD – Inhalable RNA Therapeutics for Targeted Treatment of Lung Diseases” has been honored with the Lower Saxony Innovation Award 2025. The team of researchers from Hannover Medical School (MHH) and the Fraunhofer Institute for Toxicology and Experimental Medicine ITEM received the award in the category “Knowledge and Technology Transfer.”

 

Fraunhofer-Institut für Zelltherapie und Immunologie, Institutsteil Bioanalytik und Bioprozesse IZI-BB

Yokogawa and Fraunhofer IZI-BB integrate single-cell injection with low-input, image-activated cell sorting

Yokogawa Electric Corporation and Fraunhofer IZI-BB signed a framework agreement in December 2025 to start a cooperation and streamline future joint activities. In a first project, two technologies shall be combined towards an end-to-end workflow that connects precise injection of material into single cells with downstream sorting and the establishment of clonal cell lines. Thereafter, Yokogawa aims to establish an algal cell factory.

 

Fraunhofer Research Institution for Individualized Medical Technology and Engineering IMTE

DFG approves innovative MPI scanner for Lübeck – paving the way for personalized diagnostics and cancer therapy

The German Research Foundation (DFG) has approved approximately €4.3 million in funding for the University of Lübeck’s proposal to develop a novel scanner for Magnetic Particle Imaging (MPI) in combination with computed tomography (CT) and hyperthermia. Magnetic Particle Imaging is a young, highly sensitive real-time imaging modality that visualizes magnetic nanoparticles in the body and is increasingly paving the way for new diagnostic and therapeutic concepts.

 

Fraunhofer Institute for Biomedical Engineering IBMT

Intelligent Sensors for Quality-assured Cell Production

Fraunhofer research scientists are optimizing the manufacturing of 3D tissue models using a modular sensor platform and AI. Their solution enables continuous quality control in bioreactors and opens up new perspectives for the biotech and pharmaceutical industries - for more than just animal-free drug testing.

 

Fraunhofer-Einrichtung für Individualisierte Medizintechnik IMTE

Robotik & KI für strahlungsarme Lebereingriffe

Im Projekt SURREAL werden menschzentrierte Assistenztechnologien für die Interventionelle Radiologie entwickelt. Forschende des Universitätsklinikums Schleswig-Holstein, des Fraunhofer IMTE in Lübeck, der BEC Medical GmbH in Magdeburg und dem Fraunhofer IDMT in Oldenburg entwickeln in den kommenden drei Jahren gemeinsam eine robotergestützte Assistenzplattform, die klinische Fachkräfte während ultraschallbasierter Leberuntersuchungen und -interventionen entlastet.

 

Fraunhofer Gesundheit & vfa / 12.11.2025

PROUD: das Tool für jährliche Statuserhebungen

Im Auftrag vom vfa und Fraunhofer Gesundheit hat die Beratungsagentur Vintura im Oktober 2025 zum zweiten Mal mit dem Monitoring-Tool PROUD (Pharma FoRschung & Entwicklung ErfOlgsmessUng in Deutschland) die Qualität und Leistungsfähigkeit des Pharma-F&E-Standorts Deutschland bestimmt. Mitgewirkt haben auch zwölf Pharmaunternehmen. Die Ergebnisse wurden im November 2025 veröffentlicht.

 

Fraunhofer Institute for Biomedical Engineering IBMT

PhenoTruck®: Mobile Lab for Early Detection of Plant Pests and Pathogens in Fruit Farming and Viticulture

Pests that spread as a result of climate change pose an increasing threat to fruit farming and viticulture in Germany. Fraunhofer researchers are working with partners to develop methods for the early identification of infestations in grapevines and in apricot, apple and pear trees so as to enable timely counter-measures to be taken. A mobile lab, the PhenoTruck®, supports rapid and reliable identification of harmful organisms directly on site.

 

Fraunhofer Institute for Experimental Software Engineering IESE

Fraunhofer research project “PETRA” develops app for AI-supported therapy support during menopause

Although menopause – also known as perimenopause – can significantly impair women's well-being and performance, medical education and support have often been inadequate to date. As part of the joint project “PETRA: AI-supported, educational therapy support for perimenopause,” researchers are now developing an AI-supported app that offers personalized information to affected women, thereby helping to improve their symptoms. 

 

Fraunhofer Institute for Digital Medicine MEVIS

Using Artificial Intelligence to Detect Changes in Lung Tumors with Greater Speed and Precision

Regular follow-up monitoring is crucial when it comes to treating cancer successfully. In the SPIRABENE project, Fraunhofer Institute for Digital Medicine MEVIS developed a deep learning-based software program which makes it possible to identify disease- and treatment-related changes in tumors in CT images with even greater speed and accuracy, thus improving the chances of recovery and making day-to-day clinical practice easier.

 

Pharma- und Medizintechnikdialog / 12.11.2025

Pharma- und Medizintechnikstrategie der Bundesregierung gestartet – Fraunhofer Gesundheit bringt angewandte Forschungsperspektive ein

 

Fraunhofer Institute for Cell Therapy and Immunology IZI

Advances in Cancer Treatment: CAR T Cells Fight Solid Tumors

A new generation of CAR T cell therapy is bringing hope in the fight against cancer, targeting not only blood cancers but also solid tumors such as ovarian and breast cancer. Fraunhofer researchers teamed up with the University Hospital of Würzburg to streamline the complicated process of manufacturing these therapies as well. This could make them much more available.

 

Fraunhofer Gesundheit & vfa

Miniature Hearts: Cardiac Organoids With an Immune System

Multicellular human cardiac organoids for drug research. The development of novel therapeutics offer great hope for the fight against widespread diseases such as cancer, but they can impair the cardiovascular system, so development often fails early on. Researchers from the Fraunhofer Institute for Toxicology and Experimental Medicine ITEM and Hannover Medical School have developed a complex cardiac organoid model that can be used to study the potential cardiotoxicity of new medications. Their miniature heart even has an immune system of its own.

 

Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering IMTE

Opening of an accredited test laboratory for additive manufacturing in medicine at Fraunhofer IMTE

The Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering IMTE today officially opened its new testing laboratory for additive manufacturing in medicine. The official opening was performed by Julia Carstens, State Secretary in the Ministry of Economic Affairs, Transport, Employment, Technology and Tourism of the State of Schleswig-Holstein, and the President of the University of Lübeck, Prof. Dr. Helge Braun.

Fraunhofer Institute for Cell Therapy and Immunology IZI

Innovative approach to minimising severe side effects after blood stem cell transplantation reaches important milestone

Researchers at the Fraunhofer Institute for Cell Therapy and Immunology (IZI) have developed a novel strategy for preventing severe side effects after haematopoietic cell transplantation – a key treatment method for various forms of blood cancer. The results have now been published in one of the most renowned haematology journals, BLOOD.

Fraunhofer Institute for Cell Therapy and Immunology IZI

Improved predictability of treatment outcomes and side effects of personalized cancer immunotherapies

A translational study led by Fraunhofer IZI and Leipzig University Hospital has yielded new insights into the efficacy and side effects of two CAR-T cell therapies targeting the B-cell maturation antigen (BCMA) in patients with refractory multiple myeloma. In particular, they wanted to find out which molecular mechanisms influence the success of treatment with such a living drug.

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